Miniature American Shepherd: mdr1-1delta (ABCB1) mutant allele frequency (Neff et al. 2004, Table 1, studied as 'Australian Shepherd, Miniature')

as of 2026-09-20 · license: facts-only

• A 2004 convenience sample, n=56, studied under the breed's pre-2015 name.
• Allele frequency counts each chromosome independently; the carrier/affected percent figure (dogs with >=1 copy) is the more clinically relevant number for an individual dog's risk.

Source

Proceedings of the National Academy of Sciences (PNAS), via PMC — Neff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen NC (2004). Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proc Natl Acad Sci U S A 101(32):11725-11730.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC511012/
retrieved 2026-09-20

Method

Quoted verbatim from the source above.

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