4
classification schemes tested, 0 showing a significant difference
verified
Measured evidence against the 'hypoallergenic breed' claim: Nicholas 2011 found no significant Can f 1 allergen-level difference between 'hypoallergenic' and other dogs' homes under any of 4 classification schemes tested (including the AKC's own list)
as of 2026-09-07 · license: facts-only
- 94.2% of the 173 one-dog homes studied had detectable Can f 1 regardless of breed classification.
- Detroit-area WHEALS cohort; a specific US regional sample, not a national or international one.
Source
OceanSide Publications (American Journal of Rhinology & Allergy), via PMC — Nicholas CE, Wegienka GR, Havstad SL, Zoratti EM, Ownby DR, Johnson CC (2011). Dog allergen levels in homes with hypoallergenic compared with nonhypoallergenic dogs. American Journal of Rhinology & Allergy 25(4):252-6.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680143/
retrieved 2026-09-07
Method
Quoted verbatim from the source above.